San Francisco 49ers
| San Francisco 2025 Schedule | |||||
| Week | Opponent | Result | Score | Record | |
|---|---|---|---|---|---|
| 1 |  | @ Green Bay | L | 20-34 | 0-1 |
| 2 |  | MIAMI | W | 25-6 | 1-1 |
| 3 |  | NEW ORLEANS | W | 34-30 | 2-1 |
| 4 |  | @ Buffalo | L | 24-41 | 2-2 |
| 5 |  | CHICAGO | W | 34-20 | 3-2 |
| 6 |  | @ LA Rams | L | 21-24 | 3-3 |
| 7 |  | SEATTLE | W | 20-17 | 4-3 |
| 8 |  | @ Dallas | W | 24-14 | 5-3 |
| 9 |  | NEW ENGLAND | L | 13-30 | 5-4 |
| 10 |  | LA CHARGERS | L | 28-31 | 5-5 |
| 11 |  | @ Arizona | W | 38-17 | 6-5 |
| 12 |  | @ Detroit | W | 21-14 | 7-5 |
| 13 |  | MINNESOTA | W | 38-28 | 8-5 |
| 14 |  | @ NY Jets | |||
| 15 | | ARIZONA | |||
| 16 | | @ Seattle | |||
| 17 | | LA RAMS | |||
